PAR7 PHARMACOECONOMICS OF COX-2-SELECTIVE INHIBITORS VERSUS NON-SELECTIVE NSAIDS AND CONCOMITANT COUMARIN USE: ECONOMIC EVALUATION LINKED TO A CASECONTROL STUDY

2-aryl quinolines related to some nsaids are selective cox-2 inhibitors

Cyclooxygenase (COX-2) selective inhibitors. Any better than NSAIDs?

Design, Synthesis and Biological Evaluation of Novel Peptide-Like Analogues as Selective COX-2 Inhibitors

A new series of peptide-like derivatives containing different aromatic amino acids andpossessing pharmacophores of COX-2 inhibitors as SO2Me or N3 attached to the para positionof an end phenyl ring was synthesized for evaluation as selective cyclooxygenase-2 (COX-2)inhibitors. The synthetic reactions were based on the solid phase peptide synthesis methodusing Wang resin. One of the analogues, i...

Design, Synthesis and Biological Evaluation of Novel Peptide-Like Analogues as Selective COX-2 Inhibitors

A new series of peptide-like derivatives containing different aromatic amino acids andpossessing pharmacophores of COX-2 inhibitors as SO2Me or N3 attached to the para positionof an end phenyl ring was synthesized for evaluation as selective cyclooxygenase-2 (COX-2)inhibitors. The synthetic reactions were based on the solid phase peptide synthesis methodusing Wang resin. One of the analogues, i...

Ocular Inflammation and Nsaids: an Overview with Selective and Non-selective Cox Inhibitors

Inflammation is a complex biological response and like other parts of the body, ocular inflammation could have untoward effects on vision if not detected and/or diagnosed early. NSAIDs are the major ocular therapeutics for treating such eye inflammations and preferred over corticosteroids. NSAIDs are given orally as well as topically to treat ocular inflammations, however topical route is prefe...